Found Zoloft and cognitive behavioral therapy to be highly effective in the treatment of reasonably severe anxiety disorders in children and adolescents. I reported on the findings when they first appeared, hailing them as mostly good news, and promised to come back with further postings about the limitations of the research. Today: thoughts about the medication arm of the trial. The is selective when it comes to research studies in psychiatry. I suspect that the editors chose this paper because it looked at a large sample (489 subjects) and because the results were striking. The children had social anxiety, generalized anxiety, and separation anxiety. On medication, most kids responded, and the responses were substantial. Sertraline is used for a number of conditions, including major depressive disorder (MDD), obsessive–compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder, and social anxiety disorder (SAD). The comparative efficacy of sertraline and TCAs for melancholic depression has not been studied. A 1998 review suggested that, due to its pharmacology, sertraline may be more efficacious than other SSRIs and equal to TCAs for the treatment of melancholic depression. A meta-analysis of 12 new-generation antidepressants showed that sertraline and escitalopram are the best in terms of efficacy and acceptability in the acute-phase treatment of adults with unipolar MDD. Sertraline used for the treatment of depression in elderly (older than 60) patients was superior to placebo and comparable to another SSRI fluoxetine, and TCAs amitriptyline, nortriptyline (Pamelor) and imipramine. Sertraline had much lower rates of adverse effects than these TCAs, with the exception of nausea, which occurred more frequently with sertraline. In addition, sertraline appeared to be more effective than fluoxetine or nortriptyline in the older-than-70 subgroup. placebo in elderly patients showed a statistically significant (that is, unlikely to occur by chance), but clinically very modest improvement in depression and no improvement in quality of life. A meta-analysis on SSRIs and SNRIs that look at partial response (defined as at least a 50% reduction in depression score from baseline) found that sertraline, paroxetine and duloxetine were better than placebo.
Sertraline oral tablet is a prescription drug that’s available as the brand-name drug Zoloft. This drug may be used as part of a combination therapy. In some cases, they may not be available in every strength or form as the brand-name version. This drug is used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. This means you may need to take it with other medications. This drug belongs to a class of drugs called selective serotonin reuptake inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. This drug works by increasing the amount of serotonin, a natural substance in your brain, that helps maintain mental health balance. There are 11 references cited in this article, which can be found at the bottom of the page. She received her Associates Degree in Nursing from Olney Central College in 1987. Calibrating Your Dosage Taking Zoloft Safely Combining Zoloft with Other Medical Therapies Community Q&A11 References When used properly, Zoloft can greatly improve the quality of life for people suffering from depression, anxiety, panic disorders, and other conditions. Zoloft, also known as sertraline, is a selective serotonin reuptake inhibitor (SSRI) drug. If you are currently taking Zoloft, work with both your primary doctor and your therapist to determine a dosage regimen that fits your needs. If you increase your dosage, do so slowly under your doctor’s supervision, and watch out for any possible side effects.
Learn more about ZOLOFT® sertraline HCl, a prescription treatment for. Move Forward with Brand-Name ZOLOFT. Choose dosage from the drop down. Sertraline, sold under the trade name Zoloft among others, is an antidepressant of the selective. The comparative efficacy of sertraline and TCAs for melancholic depression. It is generally accepted that the sertraline dosages necessary for the effective treatment of OCD are higher than the usual dosage for depression.