Metoprolol is used for a number of conditions, including hypertension, angina, acute myocardial infarction, supraventricular tachycardia, ventricular tachycardia, congestive heart failure, and prevention of migraine headaches. receptors in the heart, metoprolol is also prescribed for off-label use in performance anxiety, social anxiety disorder, and other anxiety disorders. Metoprolol is sold in formulations that can be taken by mouth or given intravenously. Side effects, especially with higher doses, include dizziness, drowsiness, fatigue, diarrhea, unusual dreams, trouble sleeping, depression, and vision problems. Metoprolol may also reduce blood flow to the hands or feet, causing them to feel numb and cold; smoking may worsen this effect. Due to the high penetration across the blood-brain barrier, lipophilic beta blockers such as propranolol and metoprolol are more likely than other less lipophilic beta blockers to cause sleep disturbances such as insomnia and vivid dreams and nightmares. Serious side effects that are advised to be reported immediately include symptoms of bradycardia (resting heart rate slower than 60 beats per minute), persistent symptoms of dizziness, fainting and unusual fatigue, bluish discoloration of the fingers and toes, numbness/tingling/swelling of the hands or feet, sexual dysfunction, erectile dysfunction, hair loss, mental/mood changes, depression, breathing difficulty, cough, dyslipidemia and increased thirst. OBJECTIVESTo compare the hemodynamic effects of twice daily metoprolol tartrate (MT) and once daily metoprolol succinate (MS) in congestive heart failure patients. BACKGROUNDAdverse hemodynamic effects with MT demonstrated during initiation persist with drug readministration during chronic therapy. METHODSPatients were randomly assigned to 6.25 mg MT or 25 mg MS orally and the dose was gradually increased to a target of 50 mg twice a day or 100 mg once a day, respectively. Hemodynamic measurements were obtained at baseline and after three months of therapy—both before and after drug readministration. RESULTSLong term metoprolol therapy produced significant functional, exercise and hemodynamic benefits with no difference in response between either metoprolol preparation in the 27 patients (MT , MS ). When full dose metoprolol was readministered during chronic therapy, there were parallel adverse hemodynamic effects in both drug groups.
Davis’s Drug Guide with Updates includes drug monographs for thousands of medications from the new 16th edition update, regularly revised to keep you current. Quickly answer questions about dosing, administration and patient safety. Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you. In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should first check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.
Conclusions— This trial did not provide evidence in favor of prophylactic ICD implantation in patients with DCM of recent onset and impaired left ventricular ejection fraction." Again, make sure this matches your husband's criteria. If he's had it longer, or is presenting with other issues you haven't stated here such as a high load of PVCs or other arrhythmia, this conclusion would not apply to him. Also consider the age of the study, things may have changed since then. I do have HBP and was on a BP med at the time of the onset of pvc's. I am now on coreg 6.25mg twice a day it is controlling the BP but still having those darn pvc's can anybody help I'm not sure if I can live the rest of my life with this feeling of my heart flopping around inside me!!!!!!!!!!!!!!!! The best beta blocker for rapid heart rate, anxiety and skipped beats that occur with rapid heart rate 5-HT1 (serotonin receptor) antagonism may contribute to reduced anxiety Also blocks physical anxiety manifestations like sweating and tremor Good for POTS/IST due to sympatholythic and vasoconstricting effects. As many of you in this community are well aware, I have been suffering from troublesome episodes of sinus tachycardia for quite some time. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat. If your doctor decides you should no longer use this drug, he or she may direct you to gradually decrease your dose over 1 to 2 weeks. When gradually stopping this medication, it is recommended that you temporarily limit physical activity to decrease strain on the heart. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat. Show More This medication is a beta-blocker used to treat chest pain (angina), heart failure, and high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Metoprolol succinate extended-release tablets once daily. A 50 mg dose of immediate release metoprolol t.i.d. produced a peak plasma level of metoprolol similar to the peak level observed with 200 mg of metoprolol succinate extended-release tablet. A 200 mg dose of metoprolol succinate extended- Find patient medical information for Metoprolol Succinate Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.