Asthma is one of the most common respiratory illnesses worldwide. Furthermore, at least one to two per cent of all pregnant women experience something known as maternal asthma, making it a common complication during pregnancy. Another problem many pregnant women face is inflammatory bowel disease, which causes serious problems in the large intestine. Both these conditions are often treated by steroid medications such as prednisone. Learn all about the benefits and side-effects of prednisone treatment during pregnancy. Prednisone is a corticosteroid which can be either given orally or through a nebuliser. This drug lowers the concentration of inflammation-causing molecules in the body. This medication is used to treat conditions affecting various parts of the body, allergies, including hormonal imbalances, connective tissue problems, ulcerative colitis, heart conditions, asthma, arthritis, and so on. The objective of this study was to assess pregnancy outcome in women with a history of refractory antiphospholipid antibody–associated pregnancy loss(es) who were treated with early low-dose prednisolone in addition to aspirin and heparin. Eighteen women with antiphospholipid antibodies who had refractory pregnancy loss(es) were given prednisolone (10 mg) from the time of their positive pregnancy test to 14 weeks' gestation. Before low-dose prednisolone was given as treatment, 4 (4%) of 97 pregnancies had resulted in live births. Among 23 pregnancies supplemented with prednisolone, 9 women had 14 live births (61%), including 8 uncomplicated pregnancies. The remainder were complicated by preterm delivery, preeclampsia, and/or small-for-gestational-age infants. There were 8 first-trimester miscarriages and 1 ectopic pregnancy. There were no fetal deaths after 10 weeks' gestation and no evidence of maternal morbidity.
This sheet talks about exposure to oral prednisone or prednisolone in a pregnancy or while breastfeeding. This information should not take the place of medical care and advice from your healthcare provider. Prednisone and prednisolone belong to a group of medications called corticosteroids. In the body, prednisone is broken down into prednisolone. Prednisone and prednisolone are used to treat many conditions, such as: asthma, autoimmune diseases and skin conditions. They help to prevent or suppress inflammation (swelling and irritation) and immune responses. Prednisone and prednisolone are prescribed in a wide range of doses, depending on what condition is being treated. In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. Using prednisone or prednisolone is not expected to significantly increase this background chance. Prednisolone is a type of medicine known as a corticosteroid or steroid. Corticosteroids are not the same as anabolic steroids. Prednisolone is used to treat a wide range of health problems including allergies, blood disorders, skin diseases, infections, certain cancers and to prevent organ rejection after a transplant. It also damps down your immune system, which can help in autoimmune illnesses like rheumatoid arthritis, where your immune system mistakenly attacks its own tissues. Prednisolone is available only on prescription as tablets and as a liquid to drink. It can also be given by injection but this is usually only done in hospital. It's important to take prednisolone as your doctor has advised. The usual dose varies between 5mg and 60mg daily - 1ml of liquid prednisolone is usually equal to 10mg.
Sep 29, 2017. Advice and warnings for the use of Prednisolone during pregnancy. FDA Pregnancy Category C - Risk cannot be ruled out. Advice and warnings for the use of Prednisone during pregnancy. Use of prednisolone active metabolite at high doses for an extended period of time 30 mg/day.